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KMID : 0363420230370030049
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Journal of Korean Oriental Pediatrics
2023 Volume.37 No. 3 p.49 ~ p.74
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Trends in Animal Experiments for Herbal Medicine Treatment of Atopic Dermatitis: During the 10 year’s results
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Jeong A-Ram
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Abstract
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Objectives : The aim of this study was to analyze the research trends in herbal medicine as a treatment for atopic dermatitis (AD) in an animal model.
Methods : We conducted a search targeting papers published from 2013 onwards in Korean and English databases. The
search terms were focused on “AD”, “dermatitis”, and “Korean medicine”. Only animal experimental studies involving the oral administration of single or complex prescriptions of Korean medicine were included, whereas in vitro studies, local administration studies, and studies of specific components of Korean medicine were excluded. We searched the PubMed and Embase databases for English databases and the Science on Research Information Sharing Service (RISS) and Korean Studies Information Service System (KISS) databases for Korean studies.
Results : Among the herbal medicine intervention groups, the most commonly used single herbs were baekseonpi, danggui, and douchi, whereas a mixture of hwangryun and gamcho was used in three studies, making it the most frequently used combination. There were significant improvements in indicators related to the symptoms of AD and various
pro-inflammatory markers.
Conclusions : These results indicate the efficacy of herbal medicines in the treatment of AD in animal models. However, this study had several limitations. Therefore, future systematic reviews that address these limitations and provide more
comprehensive analyses are required.
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KEYWORD
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Animal study, Atopic dermatitis, Review, Herbal medicine
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